The science behind every packet.
Here are the published studies on Bloomage’s oral hyaluronic acid, the manufacturer of our ingredient: what was studied, how, and where to read them. These studies are about the ingredient, not ETERHYDRA as a finished product.
What is hyaluronic acid.
It is a molecule present in the skin, eyes, and joints, known for its ability to retain water.
ETERHYDRA contains 200 mg of Bloomage UltraHA® sodium hyaluronate per sachet: oral grade, high purity, obtained through fermentation, and multi-molecular weight, ranging from 200 to 600 kDa.
- IngredientBloomage UltraHA® · sodium hyaluronate
- Gradeoral, high purity
- Originfermentation · vegan
- Molecular weightmultiple weights, 200–600 kDa
- Dose200 mg per sachet
Bloomage is one of the world's largest manufacturers of hyaluronic acid.
The 200 mg trial: 129 women, 12 weeks, double-blind.
Gao et al., 2023, published in Skin Research and Technology, open access. Tongji University Hospital of Skin Diseases, Shanghai, with Bloomage 300 kDa hyaluronic acid dissolved in water. Women aged 18 to 35 and 45 to 65, with dry, oily, and normal skin; placebo, 100 mg or 200 mg daily. Skin hydration, tone, thickness, and density were measured. Results in the original source.
- Designrandomized, double-blind, placebo-controlled
- Participants129 women
- Studied doses100 mg and 200 mg per day
- Duration12 weeks
- RegistrationChiCTR2300073814
Four studies with Bloomage’s hyaluronic acid, the manufacturer of our ingredient.
These are the published studies on Bloomage oral hyaluronic acid. They use different doses, formats, and molecular weights than ETERHYDRA. To learn about their results and limitations, consult the original sources.
Gao et al., 2023 · 200 mg · 12 weeks
Randomized, double-blind, placebo-controlled. 129 women aged 18 to 65, 12 weeks, Tongji University Skin Disease Hospital (Shanghai). Measured skin hydration, tone, thickness, and density. Skin Research and Technology, 2023.
A&G Laboratories, Badajoz · 150 mg · 6 months
Open-label study, without a placebo group. 29 women aged 55 to 79, 6 months, approved by the Ethics Committee of the Infanta Cristina University Hospital (Badajoz). Firmness and elasticity were measured with a cutometer. Product: HAPLEX®Plus.
Feng and colleagues, Bloomage · 120 mg · 45 and 180 days
Double-blind and placebo-controlled. Skin hydration at 45 days and antioxidant markers at 180 days, in adults aged 30 to 65 years. Bloomage Freda and Shandong University.
Hibino and colleagues, Japan · 100–150 mg · 8 weeks
Randomized, double-blind, placebo-controlled. 36 women aged 30 to 60, 8 weeks. Measured hydration, elasticity, and transepidermal water loss. Anti-Aging Medicine.
What is being investigated about oral hyaluronic acid.
The absorption of ingested hyaluronic acid has been studied using markers since 2008, in animal studies (Balogh et al., 2008). It is an open line of research, and you have it in the sources.
The dose, declared.
Each sachet contains 200 mg of Bloomage UltraHA® sodium hyaluronate. This is stated on the label and in the certificate of analysis for each batch.
80 mg of acerola vitamin C. What we can say for sure.
About 470 mg of standardized acerola extract provides 80 mg of vitamin C per sachet: 100% of the reference intake. Claims authorized by Regulation (EU) 432/2012, transcribed verbatim.
Collagen
Vitamin C contributes to the normal formation of collagen for the normal functioning of the skin.
Cellular protection
Vitamin C contributes to the protection of cells from oxidative damage.
Defenses
Vitamin C contributes to the normal functioning of the immune system.
What you can check.
Batch certificate
Each box has its batch number. Each batch, its certificate of analysis. Ask for it and we'll send it to you.
Declared composition
No patented mixtures. Each quantity is listed on the label.
Designed in Barcelona
Formula, dosage, and labeling are decided here, with a compliance perspective.
So you can read it without us there.
- Gao Y-R et al., 2023. Skin Research and Technology 29(11): e13531. Open access. doi.org/10.1111/srt.13531
- Feng N, Shi Y, Guo F, Guo X. Effect of oral hyaluronic acid on skin hydration and antioxidant activity. Bloomage Freda Biopharm and Shandong University, 2016.
- A&G Laboratories. Clinical study of HAPLEX®Plus (Bloomage Freda). Don Benito, Badajoz, 2016. Ethics Committee of the Infanta Cristina University Hospital.
- Hibino S et al. Anti-Aging Medicine 21(2): 33–38.
- Balogh L et al., 2008. Journal of Agricultural and Food Chemistry 56(22): 10582–10593.
- Regulation (EU) 432/2012, authorized vitamin C claims.
These are studies on the ingredient, not on Eterhydra as a finished product.
Food supplement. Recommended daily dose: 1 sachet per day. Do not exceed the expressly recommended daily dose. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Keep out of reach of young children. Contains xylitol: excessive consumption may have a laxative effect. Consult your doctor if you are pregnant, breastfeeding, or undergoing treatment.
Beauty that starts within.